The Science

Blood tests capture a moment.
The face captures a trend.

Hormonal transitions unfold over months. A single blood draw shows one data point. Facial biomarkers reflect cumulative change, making them fundamentally different from any lab test.

0%
Intra-day hormone variability
A "normal" blood test at 9am could read as "abnormal" by 3pm. This is why single draws are unreliable for tracking perimenopause.
Documented diurnal variation in estradiol and FSH levels. Rannevik et al.; Prior et al., Journal of Clinical Endocrinology & Metabolism.

One snapshot vs. continuous signal

A blood test captures a single moment. Facial biomarker analysis captures the trajectory.

High
Normal
Low
Blood draw #1
"Normal"
Blood draw #2
"Normal"
Blood draw #3
"High"
Blood draw #4
"Normal"
JanMarMayJulSepNov
Blood draws (4 snapshots/year)
Facial biomarker trend (continuous)

Side by side

Blood Test
× Single point in time
× Up to 40% daily fluctuation
× "Normal" can mask transition
× Lab visit + insurance required
× Expensive to repeat monthly
× No cognitive or symptom context
VS
Facial Analysis
✓ Cumulative exposure over weeks
✓ Not affected by daily fluctuation
✓ Shows trend, not snapshot
✓ Smartphone only, no lab
✓ Repeatable monthly at zero cost
✓ Combined with cognitive + symptoms

What the face reveals

Four categories of facial parameters associated with hormonal change, each measurable by AI.

78%

Dermal Vascularity

Micro-circulation patterns in facial skin associated with estrogen changes.

65%

Periorbital Geometry

Under-eye tissue and fluid distribution shifts correlated with hormonal status.

72%

Cutaneous Texture

Collagen density, sebaceous activity, and hydration patterns responding to hormonal shifts.

58%

Volume Distribution

Facial volume loss and redistribution patterns associated with declining estrogen.

Not just the face. Three channels fused.

01

Facial Biomarkers

AI analysis of dermal, periorbital, volumetric, and cutaneous patterns from a smartphone camera.

~2 min
02

Cognitive Battery

Micro-tasks measuring attention, memory, processing speed. Calibrated to hormonal sensitivity.

~5 min
03

Symptom Capture

70+ symptom domains with algorithm-driven pattern detection across hormonal clusters.

~3 min

See it for yourself.

Try a free personal check, or explore how MARKABLE works for your organization.

Try Your Free Personal Check For Clinics For Employers

MARKABLE is a general wellness product for personal awareness and self-monitoring only. It is not a medical device and is not intended to diagnose, treat, cure, or prevent any disease or medical condition. Always consult a qualified healthcare provider for medical advice.